Python Job: (Junior) Scientist Spectral Imaging

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Job Skills

Company

Roche

Location

Basel - Switzerland

Job type

Full-Time

Python Job Details

The Position

As a (Junior)Scientist Spectral Imaging in the section Particle & Formulation Characterization within the Solid State Sciences Department for Technical Development of

Synthetic Molecules you are responsible for developing analytical methods which will provide spectral imaging insights and additional information to improve process
understanding, drug substance and drug product development and product quality.

Our mission as the Section for Particle & Formulation Characterization is to support our project partners at the interface between chemical and pharmaceutical development in solid
analysis, e.g. thermal, particle or powder analyses as well as surface nanoanalytics. We work in strong collaboration with our colleagues from the neighboring sections Particle
Design, Solid Form Screening and Process Analytical Techniques as well as neighboring departments such as manufacturing, analytical development, quality assurance and the
registration department.


In addition to classical solid state analysis, our portfolio includes the latest analytical techniques such as atomic force microscopy, nanoindentation, RAMAN imaging, micro-
computed tomography and the determination of mechanical properties of powders, granules and tablets with various innovative equipment.

Your main responsibilities will include:
  • Apply and combine imaging technologies (e.g. hyperspectral imaging, X-ray micro- computed tomography, bright-field microscopy) with advanced data analysis in order
to extract new information about the products, improve process understanding and ensure product quality
  • Routine use of image processing and data analysis software (e.g. ImageJ, MATLAB) as well as statistical methods (e.g. Chemometrics) in support of Quality-by-Design
based development
  • Optimize image acquisition protocols and workflows for data analysis, visualization, interpretation and documentation
  • Develop and coach technicians and scientists in various ranges of imaging technologies and data analysis
  • Provide mentorship as a subject-matter expert and be responsible for the field of imaging within Synthetic Molecules Technical Development
  • Extend the current applications of imaging technologies for drug product development in close collaboration with internal customers and partners
  • Scout, evaluate and implement new imaging technologies and data analysis
  • Next to spectral imaging, performing routine analysis in various analytical techniques within the section during about 40% of the work time is expected

What do you bring?
You ideally hold a Master or PhD in a scientific discipline with a strong focus on imaging technologies (e.g., hyperspectral imaging, X-ray micro-computed tomography,
bright-field microscopy) and vibrational spectroscopy (e.g., Raman) as well as the corresponding data processing and quantitative analysis methods (e.g., ImageJ, MATLAB).

Other key requirements we are looking for are:
  • You have gained initial experience in the field of powder characterization
  • You are interested in the latest analytical techniques in the field of solid state
development and are willing to further familiarize yourself with them
  • You have very good computer skills and a talent for digital technologies
  • You have knowledge in programming (e.g., R, Matlab, VBA, Python, R programming etc.) to program your own small apps
  • You are a self starter who optimizes processes, undertakes projects and develops new skills on your own initiative
  • You are an excellent team player, reliable, flexible and remain calm even in stressful situations
  • You are open to new ways of working and support our team on the way to more flexibility and agility
  • You speak German and can communicate fluently in English

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.

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